Yes. The DUI law in Pennsylvania makes it a crime to drive while there is marijuana in your blood. The DUI statute does not differentiate “medical marijuana” from “marijuana. Recently, there have been several cases decided by our Superior Court that show there might be defenses to these charges if you were using medical marijuana and followed all of the medical marijuana regulations. However, currently, it is still illegal to operate a motor vehicle with marijuana in your system whether or not it is medically prescribed.